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Article

Effect of high-dose clopidogrel according to CYP2C19*2 genotype in patients undergoing percutaneous coronary intervention- a systematic review and meta-analysis.

Thrombosis research - 1 Mar 2015

Zhang Lanning, Yang Jie, Zhu Xiaoquan, Wang Xuyun, Peng Li, Li Xiaoqi, Cheng Peng, Yin Tong

Abstract excerpt

INTRODUCTION: High-dose clopidogrel has been recommended to overcome clopidogrel non-responsiveness in patients undergoing percutaneous coronary intervention (PCI), especially those with CYP2C19 loss-of-function genotypes. However, there is controversy over the pharmacodynamics and clinical effects of the strategy. This meta-analysis was conducted to evaluate the antiplatelet effects of high-dose clopidogrel...

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Source

Identifiers

PMID: 25511576
DOI: 10.1016/j.thromres.2014.12.007

Genes

VASP
LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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