Article
Clopidogrel resistance and its effect on clinical outcomes in acute coronary syndrome.
Indian heart journal - 1 Jan 2000
Lodhi Heemanshu, Bhat Keshavamurthy Ganapathy, Guleria Vivek Singh, Pillai Ratheesh Kumar Janardhana, Goel Ribhu, Sharma Nitin, Sharma Anuka, Sharma Varun
Abstract excerpt
AIM: The genetic polymorphism of CYP2C19 influences clopidogrel metabolism and resistance. Aim was to assess the association between CYP2C19 loss of function variation, clopidogrel resistance based on platelet reactivity units and clinical outcomes. METHODS: A total of 668 patients of Acute Coronary Sundrome (ACS) who underwent Percutaneous Coronary Intervention (PCI) were subjected to genetic screening and 143...
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