Article
The Impact of CYP2C19 Loss-of-Function Polymorphisms, Clinical, and Demographic Variables on Platelet Response to Clopidogrel Evaluated Using Impedance Aggregometry.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Apr 2017
Mărginean Alina, Bănescu Claudia, Moldovan Valeriu, Scridon Alina, Mărginean Mihai, Bălaşa Rodica, Maier Smaranda, Ţăruşi Mariana, Dobreanu Minodora
Abstract excerpt
INTRODUCTION: Clopidogrel is an antiplatelet drug widely used in patients with acute coronary syndromes or stroke. Despite adequate antiplatelet therapy, some patients develop acute ischemic events. This is partly attributed to the fact that they have poor inhibition of platelet reactivity, despite treatment. This study aimed to assess the impact of clinical and demographic variables and of cytochrome P450 2C19...
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