Influence of rs5065 atrial natriuretic peptide gene variant on coronary artery disease.

doi:10.1016/j.jacc.2012.02.017

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Article

Influence of rs5065 atrial natriuretic peptide gene variant on coronary artery disease.

Journal of the American College of Cardiology - 15 May 2012

Barbato Emanuele, Bartunek Jozef, Mangiacapra Fabio, Sciarretta Sebastiano, Stanzione Rosita, Delrue Leen, Cotugno Maria, Marchitti Simona, Iaccarino Guido, Sirico Giusy, Di Castro Sara, Evangelista Anna, Lambrechts Diether, Sinnaeve Peter, De Bruyne Bernard, Van De Werf Frans, Janssens Stefaan, Fox Keith A A, Wijns William, Volpe Massimo, Rubattu Speranza

Abstract excerpt

OBJECTIVES: The aim of this study was to investigate the impact of rs5065 atrial natriuretic peptide (ANP) gene variant on coronary artery disease (CAD) and its outcomes and to gain potential mechanistic insights on the association with CAD. BACKGROUND: Either modified ANP plasma levels or peptide structural alterations have been involved in development of cardiovascular events. METHODS: Three hundred...

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PMID: 22575314
DOI: 10.1016/j.jacc.2012.02.017

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