Article
Age-dependent association of the polymorphisms in the mitochondria-shaping gene, OPA1, with blood pressure and hypertension in Korean population.
American journal of hypertension - 1 Oct 2011
Jin Hyun-Seok, Sober Siim, Hong Kyung-Won, Org Elin, Kim Bo-Young, Laan Maris, Oh Bermseok, Jeong Seon-Yong
Abstract excerpt
BACKGROUND: Essential hypertension is associated with mitochondrial dysfunction. Because mitochondrial dynamics; mitochondrial morphological changes are closely linked with various mitochondrial functions, we aimed to examine whether the genetic variation of the mitochondria-shaping genes influenced the susceptibility to blood pressure (BP) and hypertension. METHODS: The quantitative BP trait analysis and...
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