Article
Association of genetic variation in the mitochondrial genome with blood pressure and metabolic traits.
Hypertension (Dallas, Tex. : 1979) - 1 Oct 2012
Liu Chunyu, Yang Qiong, Hwang Shih-Jen, Sun Fengzhu, Johnson Andrew D, Shirihai Orian S, Vasan Ramachandran S, Levy Daniel, Schwartz Faina
Abstract excerpt
Elevated blood pressure (BP) is a major risk factor for cardiovascular disease. Several studies have noted a consistent maternal effect on BP; consequently, mitochondrial DNA variation has become an additional target of investigation of the missing BP heritability. Analyses of common mitochondrial DNA polymorphisms, however, have not found evidence of association with hypertension. To explore associations of...
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