Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts.

Scientific reports - 12 Jan 2021

Laaksonen Jaakko, Mishra Pashupati P, Seppälä Ilkka, Lyytikäinen Leo-Pekka, Raitoharju Emma, Mononen Nina, Lepistö Maija, Almusa Henrikki, Ellonen Pekka, Hutri-Kähönen Nina, Juonala Markus, Raitakari Olli, Kähönen Mika, Salonen Jukka T, Lehtimäki Terho

Abstract excerpt

High blood pressure (BP) is a major risk factor for many noncommunicable diseases. The effect of mitochondrial DNA single-nucleotide polymorphisms (mtSNPs) on BP is less known than that of nuclear SNPs. We investigated the mitochondrial genetic determinants of systolic, diastolic, and mean arterial BP. MtSNPs were determined from peripheral blood by sequencing or with genome-wide association study SNP arrays in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

Share to Finland

Share to Genome, Mitochondrial

Share to Genome-Wide Association Study

Share to Hypertension

Share to Mitochondria

Source

Open in PubMed Open full text

Identifiers

PMID: 33436758
DOI: 10.1038/s41598-020-79931-6
PMCID: PMC7804469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts.PMID 33436758Read ↗

Maternal influence on blood pressure suggests involvement of mitochondrial DNA in the pathogenesis of hypertension: the Framingham Heart Study.Semantic proximity Read ↗

Association of genetic variation in the mitochondrial genome with blood pressure and metabolic traits.Semantic proximity Read ↗

Heteroplasmic mitochondrial DNA variants in cardiovascular diseases.Semantic proximity Read ↗

Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studiesSemantic proximity Read ↗

Systematic analysis of the clinical and biochemical characteristics of maternally inherited hypertension in Chinese Han families associated with mitochondrial.Semantic proximity Read ↗

Comparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits.Semantic proximity Read ↗

Genetic variants and blood pressure in a population-based cohort: the Cardiovascular Risk in Young Finns study.Semantic proximity Read ↗

The role of mitochondrial genome in essential hypertension in a Chinese Han population.Semantic proximity Read ↗

Mitochondrial genome mutations in hypertensive individuals.Semantic proximity Read ↗

Relations of mitochondrial genetic variants to measures of vascular function.Semantic proximity Read ↗

Age-dependent association of the polymorphisms in the mitochondria-shaping gene, OPA1, with blood pressure and hypertension in Korean population.Semantic proximity Read ↗

Mitochondrial genome single nucleotide polymorphisms and their phenotypes in the Japanese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.