Article
Maternal influence on blood pressure suggests involvement of mitochondrial DNA in the pathogenesis of hypertension: the Framingham Heart Study.
Journal of hypertension - 1 Oct 2007
Yang Qiong, Kim Sung K, Sun Fengzhu, Cui Jing, Larson Martin G, Vasan Ramachandran S, Levy Daniel, Schwartz Faina
Abstract excerpt
OBJECTIVE: To investigate the contribution of the mitochondrial genome to hypertension and quantitative blood pressure (BP) phenotypes in the Framingham Heart Study cohort, a randomly ascertained, community-based sample. METHODS: Longitudinal BP values of 6421 participants (mean age, 53 years; 46% men) from 1593 extended families were used for analyses. In analyses of BP as a continuous trait, a variance...
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