Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of polymorphisms in transforming growth factor-β receptors with susceptibility to gastric cardia adenocarcinoma.

Molecular biology reports - 1 Apr 2012

Guo Wei, Dong Zhiming, Guo Yanli, Chen Zhifeng, Yang Zhibin, Kuang Gang

Abstract excerpt

Both transforming growth factor-β receptor I (TGFBR1) and receptor II (TGFBR2) are serine/threonine kinases and play important roles in TGF-β/Smads signal pathway. The case-control study was performed to evaluate the possible association of Int7G24A and *6A polymorphisms of TGFBR1 and G-875A polymorphism of TGFBR2 with susceptibility to gastric cardia adenocarcinoma (GCA) in a population of North China....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Cardia
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Serine-Threonine Kinases

Share to Receptor, Transforming Growth Factor-beta Type I

Share to Receptor, Transforming Growth Factor-beta Type II

Share to Receptors, Transforming Growth Factor beta

Share to Stomach Neoplasms

Source

Identifiers

PMID: 21785915
DOI: 10.1007/s11033-011-1217-0

Genes

GCA
TGFBR1
TGFBR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of polymorphisms in transforming growth factor-β receptors with susceptibility to gastric cardia adenocarcinoma.PMID 21785915Read ↗

Polymorphisms of transforming growth factor-β1 associated with increased risk of gastric cardia adenocarcinoma in north China.Semantic proximity Read ↗

Association between the TGFB1 -509C/T and TGFBR2 -875A/G polymorphisms and gastric cancer: a case-control studySemantic proximity Read ↗

TGFBR1 tagging SNPs and gastric cancer susceptibility: a two-stage case-control study in Chinese population.Semantic proximity Read ↗

Genetic variations in the TGFβ signaling pathway, smoking and risk of colorectal cancer in a Chinese population.Semantic proximity Read ↗

Influence of TGFB1 C-509T polymorphism on gastric cancer risk associated with TGF-β1 expression in the gastric mucosa.Semantic proximity Read ↗

A low-frequency variant in SMAD7 modulates TGF-β signaling and confers risk for colorectal cancer in Chinese population.Semantic proximity Read ↗

TGFB1 and TGFBR2 functional polymorphisms and risk of esophageal squamous cell carcinoma: a case-control analysis in a Chinese population.Semantic proximity Read ↗

Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population.Semantic proximity Read ↗

Genetic polymorphisms of transforming growth factor-beta1 and its receptors and colorectal cancer susceptibility: a population-based case-control study in China.Semantic proximity Read ↗

TGF-α gene variations and increased susceptibility of gastric cancer in an Eastern Chinese Han population.Semantic proximity Read ↗

Impact of TGF-β1 expression and -509C>T polymorphism in the TGF-β1 gene on the progression and survival of gastric cancer.Semantic proximity Read ↗

Association between TGFBR1 polymorphisms and cancer risk: a meta-analysis of 35 case-control studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.