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Article

Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population.

International journal of cancer - 15 Mar 2007

Jin Guangfu, Wang Lina, Chen Wensen, Hu Zhibin, Zhou Yan, Tan Yongfei, Wang Jianming, Hua Zhaolai, Ding Weiliang, Shen Jing, Zhang Zuofeng, Wang Xinru, Xu Yaochu, Shen Hongbing

Abstract excerpt

Growing evidence suggests that the transforming growth factor beta (TGF-beta) signaling pathway occupies a central position in the signaling networks that control cell growth and differentiation. TGF-beta1 and its receptor TGF-betaRII have been correlated with the development of certain forms of cancer, including gastric cancer. We hypothesized that functional genetic variants in TGFB1 and TGFBR2 are associated...

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Source

Identifiers

PMID: 17187359
DOI: 10.1002/ijc.22443

Genes

TGFB1
TGFBR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population.PMID 17187359Read ↗

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