Article
Influence of TGFB1 C-509T polymorphism on gastric cancer risk associated with TGF-β1 expression in the gastric mucosa.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Jul 2015
Choi Yoon Jin, Kim Nayoung, Shin Aesun, Lee Hye Seung, Nam Ryoung Hee, Chang Hyun, Shin Cheol Min, Park Young Soo, Lee Dong Ho, Park Ji Hyun, Jung Hyun Chae
Abstract excerpt
BACKGROUND: Transforming growth factor-β1 (TGF-β1) has dual roles inhibiting and promoting carcinogenesis. Although many researchers have conducted association studies between TGFB1 C-509T polymorphism and the risk of developing gastric cancer, the results are not uniform. METHODS: We genotyped 1028 gastric cancer patients and 958 controls by the polymerase chain reaction-restriction fragment length polymorphism...
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