Article
Identification and characterization of acyclovir-resistant clinical HSV-1 isolates from children.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Oct 2011
Wang Yi, Wang Qi, Zhu Qinchang, Zhou Rong, Liu Jinsong, Peng Tao
Abstract excerpt
BACKGROUND: The occurrence of herpes simplex virus (HSV) with acyclovir (ACV) resistance is a cause for concern due to the frequent use of ACV for treatment, suppressive therapy, and prophylaxis of HSV infection. Although HSV infection is prevalent among children, very little is known about the drug susceptibility of HSV circulating in this patient population. OBJECTIVE: To determine the status of ACV resistant...
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