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Article

Resistance of herpes simplex viruses to acyclovir: an update from a ten-year survey in France.

Antiviral research - 1 Nov 2014

Frobert Emilie, Burrel Sonia, Ducastelle-Lepretre Sophie, Billaud Geneviève, Ader Florence, Casalegno Jean-Sébastien, Nave Viviane, Boutolleau David, Michallet Mauricette, Lina Bruno, Morfin Florence

Abstract excerpt

The widespread use of acyclovir (ACV) and the increasing number of immunocompromised patients have raised concern about an increase in ACV-resistant herpes simplex virus (HSV). ACV resistance has traditionally been a major concern for immunocompromised patients with a frequency reported between 2.5% and 10%. The aim of this study was to reassess the status of HSV resistance to ACV in immunocompetent and...

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Identifiers

PMID: 25218782
DOI: 10.1016/j.antiviral.2014.08.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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