Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for Age As a Modifier of Genetic Associations for Lipid Levels

21 Jul 2011

Abstract excerpt

In order to identify novel genetic variants that influence plasma lipid concentrations, we performed a genome-wide association study (GWAS) comprised of 411 children under 18 years of age, ascertained at St. Jude Children's Research Hospital, all of whom were of European, African, or Mexican descent. Promising associations (p < 10(-5)) were subsequently examined in 1040 additional youths and 3508 adults from the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Genetic Associations and Epidemiology
Share to Nutrition, Genetics, and Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21777205
DOI: 10.1111/j.1469-1809.2011.00664.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for Age As a Modifier of Genetic Associations for Lipid LevelsPMID 21777205Read ↗

Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study.Semantic proximity Read ↗

Associations of genetic variants for adult lipid levels with lipid levels in children. The Generation R Study.Semantic proximity Read ↗

Evaluation of the gene-age interactions in HDL cholesterol, LDL cholesterol, and triglyceride levels: the impact of the SORT1 polymorphism on LDL cholesterol levels is age dependent.Semantic proximity Read ↗

Evidence of differential allelic effects between adolescents and adults for plasma high-density lipoprotein.Semantic proximity Read ↗

Association of known loci with lipid levels among children and prediction of dyslipidemia in adults.Semantic proximity Read ↗

Associations of APOE variants with sphingomyelin and cholesterol metabolites across the life-course in diverse populations.Semantic proximity Read ↗

Common INSIG2 polymorphisms are associated with age-related changes in body size and high-density lipoprotein cholesterol from young adulthood to middle age.Semantic proximity Read ↗

Cohort Profile: The Saguenay Youth Study (SYS).Semantic proximity Read ↗

Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program.Semantic proximity Read ↗

Age-related effects of genetic variation on lipid levels: The Columbia University BioMarkers Study.Semantic proximity Read ↗

Prediction of Adult Dyslipidemia Using Genetic and Childhood Clinical Risk Factors: The Cardiovascular Risk in Young Finns Study.Semantic proximity Read ↗

Association of Maternal Age and Blood Markers for Metabolic Disease in NewbornsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.