Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of known loci with lipid levels among children and prediction of dyslipidemia in adults.

Circulation. Cardiovascular genetics - 1 Dec 2011

Tikkanen Emmi, Tuovinen Tarja, Widén Elisabeth, Lehtimäki Terho, Viikari Jorma, Kähönen Mika, Peltonen Leena, Raitakari Olli T, Ripatti Samuli

Abstract excerpt

BACKGROUND: Recent genome-wide association studies have found 95 distinct genetic loci associated with high-density (HDL-C) and low-density (LDL-C) lipoprotein cholesterol, total cholesterol (TC), and triglycerides (TG), using adult samples. It is not known if these variants are associated with lipid levels in children and adolescents and if the genetic risk score (GRS), based on these variants, could improve...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Cohort Studies

Share to Dyslipidemias

Share to Lipids

Share to Risk Factors

Share to Young Adult

Source

Identifiers

PMID: 21984478
DOI: 10.1161/CIRCGENETICS.111.960369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of known loci with lipid levels among children and prediction of dyslipidemia in adults.PMID 21984478Read ↗

Prediction of Adult Dyslipidemia Using Genetic and Childhood Clinical Risk Factors: The Cardiovascular Risk in Young Finns Study.Semantic proximity Read ↗

The Combined Effect of Common Genetic Risk Variants on Circulating Lipoproteins Is Evident in Childhood: A Longitudinal Analysis of the Cardiovascular Risk in Young Finns Study.Semantic proximity Read ↗

Associations of genetic variants for adult lipid levels with lipid levels in children. The Generation R Study.Semantic proximity Read ↗

Common genetic variants associated with lipid profiles in a Chinese pediatric population.Semantic proximity Read ↗

Role of Conventional Childhood Risk Factors Versus Genetic Risk in the Development of Type 2 Diabetes and Impaired Fasting Glucose in Adulthood: The Cardiovascular Risk in Young Finns Study.Semantic proximity Read ↗

Discovery and refinement of loci associated with lipid levels.Semantic proximity Read ↗

Genetic Risk Scores for Complex Disease Traits in Youth.Semantic proximity Read ↗

Defining the spectrum of alleles that contribute to blood lipid concentrations in humans.Semantic proximity Read ↗

Development of genome-wide polygenic risk scores for lipid traits and clinical applications for dyslipidemia, subclinical atherosclerosis, and diabetes cardiovascular complications among East Asians.Semantic proximity Read ↗

Genetic Landscape of Pediatric Dyslipidemia in a Turkish Cohort: Insights From a Single-Center Experience.Semantic proximity Read ↗

Interactions between genetic variants and dietary lipid composition: effects on circulating LDL cholesterol in children.Semantic proximity Read ↗

Adiposity significantly modifies genetic risk for dyslipidemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.