Article
Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study.
Annals of human genetics - 1 Sept 2013
Dumitrescu Logan, Carty Cara L, Franceschini Nora, Hindorff Lucia A, Cole Shelley A, Bůžková Petra, Schumacher Fredrick R, Eaton Charles B, Goodloe Robert J, Duggan David J, Haessler Jeff, Cochran Barbara, Henderson Brian E, Cheng Iona, Johnson Karen C, Carlson Chris S, Love Shelly-Ann, Brown-Gentry Kristin, Nato Alejandro Q, Quibrera Miguel, Anderson Garnet, Shohet Ralph V, Ambite José Luis, Wilkens Lynne R, Marchand Loïc Le, Haiman Christopher A, Buyske Steven, Kooperberg Charles, North Kari E, Fornage Myriam, Crawford Dana C
Abstract excerpt
Numerous common genetic variants that influence plasma high-density lipoprotein cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglyceride distributions have been identified via genome-wide association studies (GWAS). However, whether or not these associations are age-dependent ha...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.