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Article

Prediction of Adult Dyslipidemia Using Genetic and Childhood Clinical Risk Factors: The Cardiovascular Risk in Young Finns Study.

Circulation. Cardiovascular genetics - 1 Jun 2017

Nuotio Joel, Pitkänen Niina, Magnussen Costan G, Buscot Marie-Jeanne, Venäläinen Mikko S, Elo Laura L, Jokinen Eero, Laitinen Tomi, Taittonen Leena, Hutri-Kähönen Nina, Lyytikäinen Leo-Pekka, Lehtimäki Terho, Viikari Jorma S, Juonala Markus, Raitakari Olli T

Abstract excerpt

BACKGROUND: Dyslipidemia is a major modifiable risk factor for cardiovascular disease. We examined whether the addition of novel single-nucleotide polymorphisms for blood lipid levels enhances the prediction of adult dyslipidemia in comparison to childhood lipid measures. METHODS AND RESULTS: Two thousand four hundred and twenty-two participants of the Cardiovascular Risk in Young Finns Study who had participated...

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PMID: 28620070
DOI: 10.1161/CIRCGENETICS.116.001604

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