Article
Associations of genetic variants for adult lipid levels with lipid levels in children. The Generation R Study.
Journal of lipid research - 1 Dec 2016
Latsuzbaia Ardashel, Jaddoe Vincent W V, Hofman Albert, Franco Oscar H, Felix Janine F
Abstract excerpt
Lipid concentrations are heritable traits. Recently, the number of known genetic loci associated with lipid levels in adults increased from 95 to 157. The effects of these 157 loci have not been tested in children. Considering that lipid levels track from childhood to adulthood, we studied to determine whether these variants already affected lipid concentrations in a large group of 2,645 children with a median...
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