Article
Age-related effects of genetic variation on lipid levels: The Columbia University BioMarkers Study.
Pediatrics - 1 Sept 2001
Talmud P J, Berglund L, Hawe E M, Waterworth D M, Isasi C R, Deckelbaum R E, Starc T, Ginsberg H N, Humphries S E, Shea S
Abstract excerpt
OBJECTIVES: To examine the genotype:phenotype association in children compared with their parents. METHODS: Variations at 4 key gene loci, namely lipoprotein lipase (LPL S447X), hepatic lipase (HL -480C>T), cholesteryl ester transfer protein (CETP TaqIB), and apolipoprotein CIII (APOC3 -455T>C and -482C>T), were examined in children (n = 495) and their parents (n = 353) in the Columbia University BioMarkers...
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