Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program.

Atherosclerosis - 1 Jul 2014

Simino Jeannette, Kume Rezart, Kraja Aldi T, Turner Stephen T, Hanis Craig L, Sheu Wayne, Chen Ida, Jaquish Cashell, Cooper Richard S, Chakravarti Aravinda, Quertermous Thomas, Boerwinkle Eric, Hunt Steven C, Rao D C

Abstract excerpt

OBJECTIVE: To detect novel loci with age-dependent effects on fasting (≥ 8 h) levels of total cholesterol, high-density lipoprotein, low-density lipoprotein, and triglycerides using 3600 African Americans, 1283 Asians, 3218 European Americans, and 2026 Mexican Americans from the Family Blood Pressure Program (FBPP). METHODS: Within each subgroup (defined by network, race, and sex), we employed stepwise linear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian
Share to Black People

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cholesterol

Share to Cholesterol, HDL

Share to Cholesterol, LDL

Share to Coronary Disease

Share to Lipids

Share to Mexican Americans

Source

Open in PubMed Open full text

Identifiers

PMID: 24819747
DOI: 10.1016/j.atherosclerosis.2014.04.008
PMCID: PMC4322916

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program.PMID 24819747Read ↗

Genetic effect on blood pressure is modulated by age: the Hypertension Genetic Epidemiology Network Study.Semantic proximity Read ↗

Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study.Semantic proximity Read ↗

Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study.Semantic proximity Read ↗

Two major QTLs and several others relate to factors of metabolic syndrome in the family blood pressure program.Semantic proximity Read ↗

Multi-center genetic study of hypertension: The Family Blood Pressure Program (FBPP).Semantic proximity Read ↗

Metabolites mediate genetic effects on disease in the Canadian Longitudinal Study on AgingSemantic proximity Read ↗

The impact of non-additive genetic associations on age-related complex diseasesSemantic proximity Read ↗

Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related DiseasesSemantic proximity Read ↗

An updated meta-analysis of genome scans for hypertension and blood pressure in the NHLBI Family Blood Pressure Program (FBPP).Semantic proximity Read ↗

Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis.Semantic proximity Read ↗

Genetic-by-age interaction analyses on complex traits in UK Biobank and their potential to identify effects on longitudinal trait change.Semantic proximity Read ↗

The impact of non-additive genetic associations on age-related complex diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.