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Article

Comparing strategies to fine-map the association of common SNPs at chromosome 9p21 with type 2 diabetes and myocardial infarction.

Nature genetics - 24 Jul 2011

Shea Jessica, Agarwala Vineeta, Philippakis Anthony A, Maguire Jared, Banks Eric, Depristo Mark, Thomson Brian, Guiducci Candace, Onofrio Robert C, Kathiresan Sekar, Gabriel Stacey, Burtt Noël P, Daly Mark J, Groop Leif, Altshuler David

Abstract excerpt

Noncoding variants at human chromosome 9p21 near CDKN2A and CDKN2B are associated with type 2 diabetes, myocardial infarction, aneurysm, vertical cup disc ratio and at least five cancers. Here we compare approaches to more comprehensively assess genetic variation in the region. We carried out targeted sequencing at high coverage in 47 individuals and compared the results to pilot data from the 1000 Genomes...

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Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Genetic Variation

Share to Genome, Human

Share to Genome-Wide Association Study

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Share to Myocardial Infarction

Source

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Identifiers

PMID: 21775993
DOI: 10.1038/ng.871
PMCID: PMC4096898

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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