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Article

Genome-wide association analysis of imputed rare variants: application to seven common complex diseases.

Genetic epidemiology - 1 Dec 2012

Mägi Reedik, Asimit Jennifer L, Day-Williams Aaron G, Zeggini Eleftheria, Morris Andrew P

Abstract excerpt

Genome-wide association studies have been successful in identifying loci contributing effects to a range of complex human traits. The majority of reproducible associations within these loci are with common variants, each of modest effect, which together explain only a small proportion of heritability. It has been suggested that much of the unexplained genetic component of complex traits can thus be attributed to...

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PMID: 22951892
DOI: 10.1002/gepi.21675
PMCID: PMC3569874

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PRDM10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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