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Scriptaid Improves <i>In Vitro</i> Development and Nuclear Reprogramming of Somatic Cell Nuclear Transfer Bovine Embryos

20 Jul 2011

Abstract excerpt

The present study evaluated the effect of Scriptaid, a novel histone deacetylase inhibitor (HDACi), on the in vitro development of somatic cell nuclear transfer (SCNT) bovine embryos. Average fluorescence intensity of two epigenetic markers (H3K9ac and H3K9m2) at two-cell, eight-cell, and blastocyst stages, and the expression levels of two developmental important genes (Oct4 and IFN-t) at the blastocyst stage...

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Identifiers

PMID: 21774687
DOI: 10.1089/cell.2011.0024

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