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Article

The impact of imputation on meta-analysis of genome-wide association studies.

PloS one - 1 Jan 2012

Li Jian, Guo Yan-fang, Pei Yufang, Deng Hong-Wen

Abstract excerpt

Genotype imputation is often used in the meta-analysis of genome-wide association studies (GWAS), for combining data from different studies and/or genotyping platforms, in order to improve the ability for detecting disease variants with small to moderate effects. However, how genotype imputation affects the performance of the meta-analysis of GWAS is largely unknown. In this study, we investigated the effects of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22496814
DOI: 10.1371/journal.pone.0034486
PMCID: PMC3320624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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