Article
Single-step capture and sequencing of natural DNA for detection of BRCA1 mutations.
Genome research - 1 Feb 2012
Thompson John F, Reifenberger Jeffrey G, Giladi Eldar, Kerouac Kristen, Gill Jaime, Hansen Erik, Kahvejian Avak, Kapranov Philipp, Knope Travis, Lipson Doron, Steinmann Kathleen E, Milos Patrice M
Abstract excerpt
Genetic testing for disease risk is an increasingly important component of medical care. However, testing can be expensive, which can lead to patients and physicians having limited access to the genetic information needed for medical decisions. To simplify DNA sample preparation and lower costs, we have developed a system in which any gene can be captured and sequenced directly from human genomic DNA without...
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