Article
Selected technologies for measuring acquired genetic damage in humans.
Environmental and molecular mutagenesis - 1 Jan 2000
Shuga Joe, Zeng Yong, Novak Richard, Mathies Richard A, Hainaut Pierre, Smith Martyn T
Abstract excerpt
Technical advances have improved the capacity to detect and quantify genetic variants, providing novel methods for the detection of rare mutations and for better understanding the underlying environmental factors and biological mechanisms contributing to mutagenesis. The polymerase chain reaction (PCR) has revolutionized genetic testing and remains central to many of these new techniques for mutation detection....
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