Article
Single molecule targeted sequencing for cancer gene mutation detection.
Scientific reports - 19 May 2016
Gao Yan, Deng Liwei, Yan Qin, Gao Yongqian, Wu Zengding, Cai Jinsen, Ji Daorui, Li Gailing, Wu Ping, Jin Huan, Zhao Luyang, Liu Song, Ge Liangjin, Deem Michael W, He Jiankui
Abstract excerpt
With the rapid decline in cost of sequencing, it is now affordable to examine multiple genes in a single disease-targeted clinical test using next generation sequencing. Current targeted sequencing methods require a separate step of targeted capture enrichment during sample preparation before sequencing. Although there are fast sample preparation methods available in market, the library preparation process is...
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