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Article

Association of osteopontin regulatory polymorphisms with systemic sclerosis.

Human immunology - 1 Oct 2011

Barizzone Nadia, Marchini Maurizio, Cappiello Francesca, Chiocchetti Annalisa, Orilieri Elisabetta, Ferrante Daniela, Corrado Lucia, Mellone Simona, Scorza Raffaella, Dianzani Umberto, D'Alfonso Sandra

Abstract excerpt

To test the involvement of osteopontin gene (OPN) in systemic sclerosis (SSc) susceptibility, two OPN single nucleotide polymorphisms previously reported to be associated with systemic lupus erythematosus, namely -156G/GG (proximal promoter) and +1239A/C (3' untranslated region (UTR)), were tested in 357 Italian patients and 864 matched control subjects. OPN serum levels were determined by enzyme-linked...

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PMID: 21763380
DOI: 10.1016/j.humimm.2011.06.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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