Article
Pharmacogenetic considerations for non-Hodgkin's lymphoma therapy.
Expert opinion on drug metabolism & toxicology - 1 Dec 2013
Espirito Santo Ana, Medeiros Rui
Abstract excerpt
INTRODUCTION: Chemotherapy is the current standard treatment for hematological malignancies for both curative and palliative purposes. Unfortunately, in the current treatment scenario chemotherapy resistance is an issue that is know to lead to a relapse in cancer. The multidrug resistance 1 (MDR1) gene is often involved in drug resistance and, so far, the best studied mechanism of resistance relates to the level...
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