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Article

Association between MDR1 C3435T polymorphism and risk of breast cancer.

Gene - 10 Dec 2013

Wang Zhaoming, Wang Ting, Bian Jianmin

Abstract excerpt

The C3435T (rs1045642) polymorphism, located in multi-drug resistance gene 1 (MDR1), has demonstrated its role in decreasing the P-gp activity level which is related to the carcinogenesis. Many published studies have evaluated the association between the MDR1 C3435T polymorphism and breast cancer risk. However, the results remain conflicting rather than conclusive. To derive a more precise estimation of the...

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ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1
Breast Neoplasms
Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Polymorphism, Single Nucleotide

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PMID: 24070710
DOI: 10.1016/j.gene.2013.09.050

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