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Article

A siRNA-based screen for genes involved in chromosome end protection.

PloS one - 1 Jan 2011

Lackner Daniel H, Durocher Daniel, Karlseder Jan

Abstract excerpt

Telomeres are nucleoprotein complexes which protect the ends of linear chromosomes from detection as DNA damage and provide a sequence buffer against replication-associated shortening. In mammals, telomeres consist of repetitive DNA sequence (TTAGGG) and associated proteins. The telomeric core co...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21760879
DOI: 10.1371/journal.pone.0021407
PMCID: PMC3121770

Genes

POT1
SNW1
TPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21760879-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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