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Article

TRF2 overexpression diminishes repair of telomeric single-strand breaks and accelerates telomere shortening in human fibroblasts

5 Mar 2007

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Share to DNA Repair Mechanisms
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Telomeres, Telomerase, and Senescence

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 17395247
DOI: 10.1016/j.mad.2007.02.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TRF2 overexpression diminishes repair of telomeric single-strand breaks and accelerates telomere shortening in human fibroblastsPMID 17395247Read ↗

Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damageSemantic proximity Read ↗

TRF2 Protects Human Telomeres from End-to-End FusionsSemantic proximity Read ↗

The Intra- and Extra-Telomeric Role of TRF2 in the DNA Damage ResponseSemantic proximity Read ↗

A RAP1/TRF2 Complex Inhibits Nonhomologous End-Joining at Human Telomeric DNA EndsSemantic proximity Read ↗

TRF1 and TRF2: pioneering targets in telomere-based cancer therapySemantic proximity Read ↗

Up-Regulation of Telomere-Binding Proteins, TRF1, TRF2, and TIN2 Is Related to Telomere Shortening during Human Multistep HepatocarcinogenesisSemantic proximity Read ↗

Role of the TRF2 Telomeric Protein in Cancer and AgingSemantic proximity Read ↗

XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening.Semantic proximity Read ↗

Mir‐23a induces telomere dysfunction and cellular senescence by inhibiting <scp>TRF</scp>2 expressionSemantic proximity Read ↗

Homologous recombination generates T-loop-sized deletions at human telomeres.Semantic proximity Read ↗

Control of Human Telomere Length by TRF1 and TRF2Semantic proximity Read ↗

Cyclin B-dependent kinase 1 regulates human TRF1 to modulate the resolution of sister telomeresSemantic proximity Read ↗

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