Article
Functional vasopressin V1 type receptors are present in variant as well as classical forms of small-cell carcinoma.
Peptides - 1 Jan 1997
North W G, Fay M J, Longo K, Du J
Abstract excerpt
Vasopressin and other neuropeptides are believed to serve as autocrine growth factors for small-cell carcinoma of the lung (SCCL), and these mitogenic influences are reported to involve increases in intracellular Ca2+. Of the classical and variant forms of SCCL, the latter is not only more drug-resistant but also refractory to vasopressin, and other peptides, with respect to changes in intracellular Ca2+. It is...
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