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Article

Specific nonpeptide photoprobes as tools for the structural study of the angiotensin II AT(1) receptor.

Journal of medicinal chemistry - 4 Nov 1999

Nouet S, Dodey P R, Bondoux M R, Pruneau D, Luccarini J M, Groblewski T, Larguier R, Lombard C, Marie J, Renaut P P, Leclerc G, Bonnafous J C

Abstract excerpt

The aim of this work was to obtain photoactivatable nonpeptide antagonists of the angiotensin II AT(1) receptor. Based on structure-function relationships, two chemical structures as well as appropriate synthetic schemes were chosen as a frame for the design of radiolabeled azido probes. The feasibility of the strategy was first assessed by the synthesis of two tritiated ligands 21 and 22 possessing a high...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10579820
DOI: 10.1021/jm991050l

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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