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Article

Paraoxonase 1 gene polymorphisms do not influence the response to treatment in Alzheimer's disease.

Dementia and geriatric cognitive disorders - 1 Jan 2011

Klimkowicz-Mrowiec A, Marona M, Spisak K, Jagiella J, Wolkow P, Szczudlik A, Slowik A

Abstract excerpt

BACKGROUND: Acetylcholinesterase inhibitors (AChEIs) are the treatment of choice for patients with Alzheimer's disease (AD). However, their efficacy is moderate and differs from patient to patient. Recent studies suggest that the Q192R variant of the paraoxonase 1 gene (PON1) might affect individ...

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Source

Identifiers

PMID: 21829028
DOI: 10.1159/000330343

Genes

APOE
PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21829028-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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