Article
Different pattern of association of paraoxonase Gln192-->Arg polymorphism with sporadic late-onset Alzheimer's disease and coronary artery disease.
Neuroscience letters - 13 Mar 2003
Scacchi Renato, Gambina Giuseppe, Martini Maria Cristina, Broggio Elisabetta, Vilardo Teresio, Corbo Rosa Maria
Abstract excerpt
The paraoxonase (PON1) Gln192-->Arg polymorphism was examined in a group of sporadic late-onset Alzheimer's disease (AD) patients, in a group of coronary artery disease (CAD) patients, and in normal subjects. The AD sample showed a PON1*R allele frequency significantly lower than the control group (0.225 vs. 0.281, P=0.049). In the CAD patients the *R allele was more frequent than in the controls (0.230 vs....
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