Article
Global distribution of malaria-resistant MHC-HLA alleles: the number and frequencies of alleles and malaria risk.
Malaria journal - 3 Sept 2014
Garamszegi László Zsolt
Abstract excerpt
BACKGROUND: The major histocompatibility complex (MHC) is the most polymorphic genetic region in vertebrates, but the origin of such genetic diversity remains unresolved. Several studies have demonstrated at the within-population level that individuals harbouring particular alleles can be less or more susceptible to malaria, but these do not allow strong generalization. METHODS: Here worldwide data on the...
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