Article
Algorithm-based prediction of HIV-1 subtype D coreceptor use.
Journal of clinical microbiology - 1 Sept 2013
Dina Julia, Raymond Stephanie, Maillard Anne, Le Guillou-Guillemette Helene, Rodalec Audrey, Beby-Defaux Agnes, Giraudeau Genevieve, Vallet Sophie, Mourez Thomas, Payan Christopher, Vabret Astrid, Ruffault Annick, Ferre Virginie, Izopet Jacques, Plantier Jean-Christophe
Abstract excerpt
We compared the coreceptor tropism-predicting performance of a specific genotypic algorithm for HIV-1 subtype D and that of the geno2pheno algorithm with different cutoffs. The D-specific algorithm and geno2pheno with a false-positivity rate cutoff of 2.5% had the same concordance with the phenotypic determination. The geno2pheno algorithm with a false-positivity rate cutoff of 2.5%, more sensitive but slightly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.