Article
Genetic susceptibility to inflammation and colonic transit in lower functional gastrointestinal disorders: preliminary analysis.
Neurogastroenterology and motility - 1 Oct 2011
Camilleri M, Carlson P, McKinzie S, Zucchelli M, D'Amato M, Busciglio I, Burton D, Zinsmeister A R
Abstract excerpt
BACKGROUND: Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) coexist in some patients. We observed an association between Crohn's disease (CD) candidate gene TNFSF15 and IBS symptom phenotype. Three genes (TLR9, IL6, and CDH1) have been associated with postinfectious (PI)-IBS. Our aim was to preliminarily assess association between 30 susceptibility loci for CD, three genes associated with...
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