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Article

Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis.

Gastroenterology - 1 Apr 2010

Villani Alexandra-Chloé, Lemire Mathieu, Thabane Marroon, Belisle Alexandre, Geneau Geneviève, Garg Amit X, Clark William F, Moayyedi Paul, Collins Stephen M, Franchimont Denis, Marshall John K

Abstract excerpt

BACKGROUND & AIMS: Acute gastroenteritis is the strongest risk factor for irritable bowel syndrome (IBS). In May 2000, >2300 residents of Walkerton, Ontario, developed gastroenteritis from microbial contamination of the municipal water supply; a longitudinal study found that >36.2% of these developed IBS. We used this cohort to study genetic susceptibility to post-infectious (PI)-IBS. METHODS: We screened 79...

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Source

Identifiers

PMID: 20044998
DOI: 10.1053/j.gastro.2009.12.049

Genes

CDH1
TLR9

Variants

rs16260
rs352139
rs5743836

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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