Article
Mice lacking urea transporter UT-B display depression-like behavior.
Journal of molecular neuroscience : MN - 1 Feb 2012
Li Xin, Ran Jianhua, Zhou Hong, Lei Tianluo, Zhou Li, Han Jingyan, Yang Baoxue
Abstract excerpt
Urea transporter B is one of urea transporters that selectively transport urea driven by urea gradient across membrane and expressed abundantly in brain. To determine the physiological role of UT-B in brain, UT-B localization, urea concentration, tissue morphology of brain, and behavioral phenotypes were studied in UT-B heterozygous mice via UT-B null mice. UT-B mRNA was expressed in olfactory bulb, cortex,...
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