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Article

Urea transporter knockout mice and their renal phenotypes.

Sub-cellular biochemistry - 1 Jan 2014

Fenton Robert A, Yang Baoxue

Abstract excerpt

Urea transporter gene knockout mice have been created for the study of the urine-concentrating mechanism. The major findings in studies of the renal phenotype of these mice are as follows: (1) Urea accumulation in the inner medullary interstitium is dependent on intrarenal urea recycling mediated by urea transporters; (2) urea transporters are essential for preventing urea-induced osmotic diuresis and thus for...

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PMID: 25298343
DOI: 10.1007/978-94-017-9343-8_9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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