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Article

Genetic approaches to studying norepinephrine function: knockout of the mouse norepinephrine transporter gene.

Biological psychiatry - 1 Nov 1999

Wang Y M, Xu F, Gainetdinov R R, Caron M G

Abstract excerpt

Norepinephrine is an important chemical messenger in the nervous system. It regulates affective states, learning and memory, endocrine and autonomic functions. It has been implicated in depression, aggression, and addiction, as well as cardiac and thermal dysregulation. The norepinephrine transporter functions by uptaking norepinephrine back into the cell for cyclic use, and is a direct target of a number of...

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PMID: 10560019
DOI: 10.1016/s0006-3223(99)00245-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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