Article
Association between the GIPR gene and the insulin level after glucose loading in schizophrenia patients treated with olanzapine.
The pharmacogenomics journal - 1 Dec 2012
Ono S, Suzuki Y, Fukui N, Sugai T, Watanabe J, Tsuneyama N, Someya T
Abstract excerpt
Several studies have shown increased rates of hyperglycemia and diabetes in schizophrenic patients treated with olanzapine. However, the underlying mechanism is poorly understood. Glucose-dependent insulinotropic polypeptide (GIP) is known to affect insulin secretion by pancreatic β cells. Recently, a meta-analysis study reported an association between a GIP receptor (GIPR) gene polymorphism (rs10423928) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
