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The Association of Olanzapine-Induced Weight Gain with Peroxisome Proliferator–Activated Receptor-γ2 Pro12Ala Polymorphism in Patients with Schizophrenia

21 Jul 2009

Abstract excerpt

Olanzapine is a second-generation antipsychotic that may cause weight gain and metabolic syndrome in some cases. The peroxisome proliferator-activated receptor (PPAR)-gamma is an important gene in the progress of type II diabetes and metabolic syndrome. In recent studies the polymorphism of the PPAR-gamma has been studied in type II diabetes mellitus, polycystic ovary syndrome, and insulin resistance syndrome. It...

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PMID: 19622037
DOI: 10.1089/dna.2009.0893

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