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Article

Association of Insulin Resistance With Schizophrenia Polygenic Risk Score and Response to Antipsychotic Treatment

3 Apr 2019

Abstract excerpt

Patients with schizophrenia show an increased risk of impaired glucose metabolism, 1 yet the mechanism behind this association remains unknown. Multiple studies have attempted to identify the determinants of insulin resistance (IR) in schizophrenia, with evidence suggesting that it cannot be fully explained by disease duration, symptom severity, medication effects, obesity, or hormonal stress axis activation, and...

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PMID: 30942838
DOI: 10.1001/jamapsychiatry.2019.0304

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