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Article

Gene Polymorphisms of Hormonal Regulators of Metabolism in Patients with Schizophrenia with Metabolic Syndrome.

Genes - 8 May 2022

Boiko Anastasiia S, Pozhidaev Ivan V, Paderina Diana Z, Mednova Irina A, Goncharova Anastasya A, Fedorenko Olga Yu, Kornetova Elena G, Semke Arkadiy V, Bokhan Nikolay A, Loonen Anton J M, Ivanova Svetlana A

Abstract excerpt

BACKGROUND: Metabolic syndrome (MetS) is a common complication of long-term treatment of persons with schizophrenia taking (atypical) antipsychotics. In this study, we investigated the existence of an association with polymorphisms of genes for four hormones that regulate energy metabolism. METHODS: We recruited 517 clinically admitted white patients (269M/248F) with a verified diagnosis of schizophrenia (ICD-10)...

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Identifiers

PMID: 35627229
DOI: 10.3390/genes13050844
PMCID: PMC9141866

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