PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.

doi:10.1111/j.1478-3231.2011.02566.x

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Article

PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.

Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2011

Petit Jean M, Guiu Boris, Masson David, Duvillard Laurence, Jooste Valerie, Buffier Perrine, Bouillet Benjamin, Brindisi Marie-Claude, Robin Isabelle, Gambert Philippe, Verges Bruno, Cercueil Jean-Pierre, Hillon Patrick

Abstract excerpt

CONTEXT: Recently, it has been shown that an allele in the adiponutrin (PNPLA3) gene was strongly associated with increased liver fat content (LFC) and liver fibrosis independent of visceral adiposity and insulin resistance. OBJECTIVE: In this study, we set out to determine whether the PNPLA3 rs738409 polymorphism was associated with liver fibrosis in unselected patients with type 2 diabetes. DESIGN, SETTING AND...

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PMID: 21745307
DOI: 10.1111/j.1478-3231.2011.02566.x

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PNPLA3

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Related research

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PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.PMID 21745307Read ↗

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PNPLA3 rs738409 C>G Variant Predicts Fibrosis Progression by Noninvasive Tools in Nonalcoholic Fatty Liver Disease.Semantic proximity Read ↗

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