Article
Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.
Gastroenterology - 1 Sept 2009
Kotronen Anna, Peltonen Markku, Hakkarainen Antti, Sevastianova Ksenia, Bergholm Robert, Johansson Lina M, Lundbom Nina, Rissanen Aila, Ridderstråle Martin, Groop Leif, Orho-Melander Marju, Yki-Järvinen Hannele
Abstract excerpt
BACKGROUND & AIMS: Our aims were to develop a method to accurately predict non-alcoholic fatty liver disease (NAFLD) and liver fat content based on routinely available clinical and laboratory data and to test whether knowledge of the recently discovered genetic variant in the PNPLA3 gene (rs738409) increases accuracy of the prediction. METHODS: Liver fat content was measured using proton magnetic resonance...
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