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Article

Immune-Related Gene Variants as Modifiers of Multiple Sclerosis Severity.

International journal of molecular sciences - 13 Jun 2026

Kulakova Olga, Baulina Natalia, Kozin Maxim, Matveeva Natalia, Boyko Alexey, Favorova Olga, Kiselev Ivan

Abstract excerpt

Multiple sclerosis (MS) is a heterogeneous autoimmune disorder of the central nervous system of polygenic nature. Uncovering the genetic predictors of MS phenotype can help to explain the nature of the disease's clinical heterogeneity, and contribute to the development of novel tools for precise disease prognosis. We conducted a retrospective genetic association study of 35 polymorphic variants in immune-related...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42353066
DOI: 10.3390/ijms27125347
PMCID: PMC13299223

Genes

CCR5
CD40
CXCR5
IL6
TCF7
EOMES
TNFRSF1A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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